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Vascular Research

Welcome to the Division of Vascular Surgery's Research Web Site. The Division of Vascular Surgery maintains an active research program that encompasses clinical trials, outcome assessment, and basic investigations in vascular disease.

The Division of Vascular Surgery actively participates in ongoing clinical trials of new device technology for the treatment of abdominal aortic aneurysms, and lower extremity ischemia ensuring that the latest options are available to patients who may be at increased risk for open surgery. Assessment of outcomes following surgical treatment of aneurysms, lower extremity occlusive disease, and carotid disease, have helped define standards of care in the field.

Finally, basic laboratory investigations focused on the mechanisms of intimal hyperplarsia and bypass graft failure round out the research activities of the division.

Basic Laboratory Investigations:

  • Role of Neuropeptide-Y in the development of bypass graft anastomotic intimal hyperplasi

Clinical Research Studies:

  •  Diabetic Foot Ulcer Studies

  • Staple 2-Aptus Study: David Deaton, MD (Principal Investigator)

    • Device – Endovascular abdominal aortic stent.
    • To evaluate the safety and efficacy of the Aptus Endovascular AAA repair system as an alternative to open surgical repair in the primary treatment of abdominal aortic aneurysms.
    • Four patients have been successfully implanted with the study device.

  • Anaconda: David Deaton, MD (Principal Investigator)

    • Device – Endovascular graft for abdominal aortic aneurysms.
    • Study was done to evaluate the technical performance of the endovascular graft in patients with infrarenal abdominal aortic aneurysms (AAA).
    • Patients participating in the study are now in follow-up. Seven patients were implanted with the Anaconda stent graft system.
    • The study is no longer enrolling patients.

  • Trivascular: David Deaton, MD (Principal Investigator)

    • Device – Endovascular graft for abdominal aortic aneurysms.
    • Patients are now in follow up. They were implanted with the endovascular graft.
    • Study is now closed to enrollment.

  • Staple-1 Aptus Study: David Deaton, MD (Principal Investigator)

    • Device – Abdominal aortic aneurysm stent with endovascular approach.
    • Phase I of the Aptus trial is now closed to enrollment. During this phase, six patients were implanted with the endovascular aortic stent.
    • The patients consisted of people with infrarenal abdominal aortic aneurysms or aorto-iliac aneurysms having suitable morphology for endovascular repair.

For additional information or inquiries please contact:

MedStar Georgetown University Hospital
Department of Surgery
Division of Vascular Surgery
3800 Reservoir Road, NW
PHC Building, 4th Floor
Washington, DC 20007

Office: 202-444-2255
Fax: 202-444-6498