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Hereditary amyloidosis

Definition

Hereditary amyloidosis is a condition in which abnormal protein deposits (called amyloid) form in almost every tissue in the body, usually the heart, kidneys, and nervous system. These protein deposits damage the tissues and interfere with how organs work.

Alternative Names

Amyloidosis - hereditary; Familial amyloidosis

Causes, incidence, and risk factors

Hereditary amyloidosis is passed down from parents to their children (inherited). For more information see: Primary amyloidosis.

Other types of amyloidosis are not inherited. They include:

  • Senile systemic, seen in patients older than 70
  • Spontaneous, which means it occurs without a known cause
  • Secondary, which means it results from diseases such as cancer of the blood cells (myeloma)

For further information, see the specific type:

Treatment

A liver treatment may be helpful. Talk to your doctor or nurse about your treatment options.

References

Gertz MA. Amyloidosis. In: Goldman L, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 194.

Review Date: 2/25/2012
Reviewed By: Jennifer K. Mannheim, ARNP, Medical Staff, Department of Psychiatry and Behavioral Health, Seattle Children's Hospital. David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M. Health Solutions, Ebix, Inc.
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